Opportunity Information: Apply for W81XWH 22 NFRP EIRA

The DoD Neurofibromatosis (NF) Early Investigator Research Award is a Department of Defense funding opportunity designed to help early-career scientists launch or strengthen a research trajectory focused on neurofibromatosis. Its core purpose is career development through a mentored research project: it supports a postdoctoral-level investigator as they design and carry out a defined NF research study, build technical and intellectual independence, and position themselves to become a future leader in the NF field. A notable feature of this award is that it explicitly welcomes promising investigators who do not yet have a background in NF research, as long as they can demonstrate strong potential and a clear commitment to pursuing a long-term career at the forefront of NF research.

A central requirement is structured mentorship. The postdoctoral investigator is the Principal Investigator (PI) on the application, but the proposal must include at least one mentor who is well matched to the project and who brings demonstrated NF expertise and mentoring capability. Mentor qualifications are expected to be evidenced through active research funding, recent publications, and a track record of successful mentorship. The opportunity also addresses practical career-stage realities: the primary mentor is allowed to be a junior faculty member, but in that scenario the PI is encouraged to add a secondary mentor with a stronger or more established record in NF research and trainee development. Across any mentoring team, reviewers are looking for a clear commitment to helping the PI progress toward independence as an NF investigator, not simply providing access to a lab or a dataset.

Administratively, this opportunity is issued by the Department of Defense, Department of the Army, through USAMRAA, under the Neurofibromatosis Research Program. The funding opportunity title is "DoD Neurofibromatosis, Early Investigator Research Award," with funding opportunity number W81XWH 22 NFRP EIRA. It is listed as a discretionary opportunity and supports science and technology and other research and development activities under CFDA 12.420. The funding instruments include both grants and cooperative agreements, indicating that awards may involve varying levels of government involvement depending on the specific award mechanism used. Eligibility is described as unrestricted, meaning it is broadly open to applicant entity types unless additional eligibility clarifications are specified elsewhere in the full announcement.

Key dates and award expectations included in the notice are a creation date of April 11, 2022, an original closing date of July 21, 2022, and an anticipated number of awards of about four. The award ceiling is listed as 0 in the source data, which typically signals that a specific maximum amount was not captured in that field and that applicants should rely on the full funding announcement for budget limits, caps, and other cost rules. Overall, the opportunity is best understood as a mentored, early-career on-ramp into NF research, emphasizing both a credible, focused project and a mentoring plan that clearly develops the PI into an independent NF researcher.

  • The Department of Defense, Dept. of the Army -- USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Neurofibromatosis, Early Investigator Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on Apr 11, 2022.
  • Applicants must submit their applications by Jul 21, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 4 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs): DoD Neurofibromatosis (NF) Early Investigator Research Award

What is the DoD Neurofibromatosis (NF) Early Investigator Research Award?

The DoD Neurofibromatosis (NF) Early Investigator Research Award is a Department of Defense funding opportunity intended to help early-career scientists launch or strengthen a research path focused on neurofibromatosis. It is structured as a career-development award built around a mentored research project.

What is the main purpose of this award?

The core purpose is career development through a mentored NF research study. The award supports a postdoctoral-level investigator in designing and carrying out a defined NF research project, building technical and intellectual independence, and positioning themselves to become a future leader in the NF field.

Who is this award designed for?

It is designed for postdoctoral-level investigators (early-career scientists) who are ready to lead a mentored research project that helps them progress toward independence as an NF investigator.

Can someone apply if they do not already have a background in neurofibromatosis research?

Yes. A notable feature is that the program explicitly welcomes promising investigators who do not yet have an NF research background, as long as they can demonstrate strong potential and a clear commitment to pursuing a long-term career at the forefront of NF research.

Is mentorship required?

Yes. A central requirement is structured mentorship. The application must include at least one mentor who is well matched to the project and who brings demonstrated NF expertise and mentoring capability.

Who serves as the Principal Investigator (PI) on the application?

The postdoctoral investigator is the Principal Investigator (PI) on the application.

What are reviewers looking for in the mentor or mentoring team?

Reviewers are looking for mentors with demonstrated NF expertise and mentoring capability, supported by evidence such as active research funding, recent publications, and a track record of successful mentorship. They also look for a clear commitment to helping the PI progress toward independence as an NF investigator, rather than simply providing access to a lab or dataset.

Can the primary mentor be a junior faculty member?

Yes. The opportunity allows the primary mentor to be a junior faculty member. However, in that scenario the PI is encouraged to add a secondary mentor with a stronger or more established record in NF research and trainee development.

Is more than one mentor allowed or expected?

The announcement requires at least one mentor, and it also discusses adding a secondary mentor in certain situations (for example, when the primary mentor is junior faculty). This implies that multi-mentor teams are acceptable and may strengthen the mentorship plan when additional experience is needed.

What kind of project does the award support?

It supports a defined neurofibromatosis research study that the postdoctoral PI designs and carries out under structured mentorship, with the explicit goal of developing independence and long-term career growth in NF research.

Which organization issues this funding opportunity?

The opportunity is issued by the Department of Defense, Department of the Army, through USAMRAA, under the Neurofibromatosis Research Program.

What is the official title of the funding opportunity?

The official title is "DoD Neurofibromatosis, Early Investigator Research Award."

What is the funding opportunity number?

The funding opportunity number is W81XWH 22 NFRP EIRA.

What type of opportunity is this (discretionary or mandatory)?

It is listed as a discretionary opportunity.

What program classification is associated with this opportunity?

It supports science and technology and other research and development activities under CFDA 12.420.

What funding instruments are used (grant, cooperative agreement, or both)?

The listed funding instruments include both grants and cooperative agreements. This means awards may involve varying levels of government involvement depending on the specific mechanism used.

What does it mean that both grants and cooperative agreements are listed?

Based on the notice, it indicates that the program may fund projects under different mechanisms, where cooperative agreements typically suggest more government involvement than standard grants. The exact level of involvement depends on the mechanism selected for a given award.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning it is broadly open to applicant entity types unless additional eligibility clarifications are specified elsewhere in the full announcement.

How many awards are expected to be made?

The anticipated number of awards is about four.

What are the key dates listed for this opportunity?

The notice lists a creation date of April 11, 2022, and an original closing date of July 21, 2022.

Is there a maximum funding amount (award ceiling)?

The award ceiling is listed as 0 in the source data. This typically signals that a specific maximum amount was not captured in that field, and applicants should rely on the full funding announcement for budget limits, caps, and other cost rules.

Where should applicants look for budget limits and cost rules?

Because the award ceiling field is not populated with a specific maximum in the provided data, applicants should refer to the full funding announcement for the official budget limits, caps, and applicable cost rules.

What is the overall emphasis of this award?

The opportunity is best understood as a mentored, early-career on-ramp into NF research that emphasizes both (1) a credible, focused project and (2) a mentoring plan that clearly develops the PI into an independent NF researcher.

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