Opportunity Information: Apply for CDC RFA CE 26 0110
The Comprehensive Addiction and Recovery Act (CARA) Community-based Coalition Enhancement Grants to Address Local Drug Crises (often referred to as the CARA Local Drug Crises Grants) is a FY 2026 discretionary grant opportunity designed to strengthen and expand the work of community coalitions that are already connected to the Drug-Free Communities (DFC) Support Program. The DFC Support Program itself was established under the Drug-Free Communities Act of 1997 (Public Law 105-20), and this CARA funding operates as an enhancement layer for communities facing especially serious drug-use challenges. The program is jointly situated within the federal drug control and public health landscape, with the Office of National Drug Control Policy (ONDCP) and the Department of Health and Human Services (HHS), through the Centers for Disease Control and Prevention (CDC) and its National Center for Injury Prevention and Control (NCIPC), accepting and administering applications.
At its core, the goal is targeted prevention for young people ages 12 to 18. The grant is meant to help communities prevent and reduce opioid use, reduce methamphetamine use, and curb the misuse of prescription drugs among local youth. Rather than funding treatment services broadly, the emphasis is on coalition-driven, community-level prevention approaches that respond to specific local drug crises. In practice, this typically means using local data to identify key drivers of youth substance use, coordinating multi-sector partners, and implementing evidence-informed strategies that can shift community norms, reduce access, improve protective factors, and ultimately lower youth use and misuse rates for the drugs named in the opportunity.
Eligibility is intentionally narrow because it is authorized under Section 103 of the Comprehensive Addiction and Recovery Act (Public Law 114-198). To apply, an organization must be a domestic public or private nonprofit entity and must be a current or former recipient of the DFC Support Program. The applicant is expected to be a community-based coalition (or an eligible organization applying on behalf of a coalition) that is actively addressing opioid, methamphetamine, and/or prescription drug misuse among youth in its area. The opportunity allows a wide range of organizational types to serve as the legal applicant, as long as they fit the nonprofit/public eligibility requirements and are tied to an established, legally recognized entity. Examples listed include state and local governments, federally recognized tribes, state-recognized tribes, urban Indian organizations (as defined in Public Law 94-437), colleges and universities, professional associations, voluntary organizations, self-help groups, consumer and provider constituency groups, community- and faith-based organizations, and tribal organizations. Nonprofits may include 501(c)(3) organizations as well as other 501(c) entities, consistent with the eligibility categories shown in the source data.
A key additional eligibility requirement is that applicants must be able to document that their community has experienced opioid misuse and/or methamphetamine use at rates higher than the national average over a sustained period. This requirement signals that the grants are meant for places where the data show an elevated, persistent burden, and where additional resources are justified to address an acute local drug crisis affecting youth. The program also makes clear that it is intended to fund coalition activities within the United States and does not authorize funding for work outside the U.S.; therefore, the applicant organization must reside in the United States and/or U.S. territories, and proposed activities are expected to occur domestically.
From an administrative standpoint, the opportunity is listed as CDC RFA CE 26 0110 under CFDA (Assistance Listing) 93.799, with CDC NCIPC as the issuing agency. The application deadline provided is January 21, 2026. The award ceiling is $75,000 per award, and the opportunity anticipates making about 45 awards. As an enhancement grant, the funding level and structure suggest it is meant to supplement and sharpen coalition work already underway through (or connected to) the DFC framework, rather than build brand-new coalitions from scratch.
The notice also states that, in alignment with the Administration's Statement of Drug Policy Priorities, applicants should be prepared to support applicable Executive Orders referenced in the announcement. The text specifically mentions Executive Order 14168 (Defending Women From Gender Ideology Extremism and Restoring Biological Truth to the Federal Government), Executive Order 14159 (Protecting the American People from Invasion), Executive Order 14173 (Ending Illegal Discrimination and Restoring Merit-Based Opportunity), Executive Order 13768 (Enhancing Public Safety in the Interior of the United States), and Executive Order 14182 (Enforcing the Hyde Amendment). The practical implication for applicants is that program planning, policies, and implementation may be expected to align with these federal directives where applicable, and applicants should read the full funding announcement carefully to understand any compliance, certification, or assurance requirements that may be tied to those orders.
In summary, this CARA funding opportunity is a focused prevention grant for established DFC-connected community coalitions working with youth ages 12-18, specifically targeting opioids, methamphetamines, and prescription drug misuse in communities with documented, above-average and sustained burden. It offers up to $75,000 to support coalition enhancement activities within the United States, with applications submitted to CDC NCIPC under a competitive process and an expected total of 45 awards for FY 2026.Apply for CDC RFA CE 26 0110
- The Centers for Disease Control - NCIPC in the health sector is offering a public funding opportunity titled "Comprehensive Addiction and Recovery Act (CARA)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.799.
- This funding opportunity was created on 2025-09-30.
- Applicants must submit their applications by 2026-01-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $75,000.00 in funding.
- The number of recipients for this funding is limited to 45 candidate(s).
- Eligible applicants include: County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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FAQs: CARA Community-based Coalition Enhancement Grants to Address Local Drug Crises (FY 2026)
What is the CARA Community-based Coalition Enhancement Grant (CARA Local Drug Crises Grant)?
It is a FY 2026 discretionary grant opportunity intended to strengthen and expand the work of community coalitions that are already connected to the Drug-Free Communities (DFC) Support Program. It functions as an enhancement layer for communities experiencing especially serious local drug-use challenges.
What is the main purpose of this funding opportunity?
The purpose is targeted youth prevention. The grant supports coalition-driven, community-level strategies to prevent and reduce opioid use, reduce methamphetamine use, and curb the misuse of prescription drugs among youth in the applicant community.
Who is the program trying to help (target population)?
The focus is on young people ages 12 to 18.
Which substances does the grant specifically target?
The opportunity specifically targets: opioids, methamphetamines, and prescription drug misuse among youth.
Is this grant meant to fund treatment services?
The emphasis is not on broadly funding treatment services. The program description centers on coalition-driven prevention approaches at the community level that respond to specific local drug crises affecting youth.
What kinds of approaches are expected under this grant?
The opportunity emphasizes coalition-driven, community-level prevention. Examples described include using local data to identify key drivers of youth substance use, coordinating multi-sector partners, and implementing evidence-informed strategies intended to shift community norms, reduce access, strengthen protective factors, and lower youth use/misuse rates for the named drugs.
Who is eligible to apply?
Eligibility is narrow. An applicant must be a domestic public or private nonprofit entity and must be a current or former recipient of the DFC Support Program. The applicant is expected to be a community-based coalition (or an eligible organization applying on behalf of a coalition) that is actively addressing opioid, methamphetamine, and/or prescription drug misuse among youth.
Does an applicant have to be connected to the Drug-Free Communities (DFC) Support Program?
Yes. The organization must be a current or former recipient of the DFC Support Program, because this CARA funding is positioned as an enhancement for DFC-connected coalition work.
Can an organization apply on behalf of a community coalition?
Yes. The description notes that the applicant may be a community-based coalition or an eligible organization applying on behalf of a coalition, as long as it meets the eligibility requirements (including being a current or former DFC recipient).
What types of organizations can serve as the legal applicant?
The opportunity indicates that a wide range of organizational types may serve as the legal applicant if they meet the domestic public/private nonprofit requirement and are tied to an established, legally recognized entity. Examples listed include state and local governments, federally recognized tribes, state-recognized tribes, urban Indian organizations (as defined in Public Law 94-437), colleges and universities, professional associations, voluntary organizations, self-help groups, consumer and provider constituency groups, community- and faith-based organizations, and tribal organizations.
Are nonprofits limited to 501(c)(3) organizations?
No. The description notes that nonprofits may include 501(c)(3) organizations as well as other 501(c) entities, consistent with the eligibility categories shown in the source data.
Are for-profit organizations eligible?
Based on the provided description, eligibility is limited to domestic public or private nonprofit entities (and DFC current/former recipients). For-profit eligibility is not indicated in the information provided.
Is there an additional eligibility requirement related to local drug-use rates?
Yes. Applicants must be able to document that their community has experienced opioid misuse and/or methamphetamine use at rates higher than the national average over a sustained period.
Does the required documentation relate to youth-only rates?
The description states that the community must document opioid misuse and/or methamphetamine use above the national average over a sustained period, and the overall program focus is youth ages 12 to 18. The information provided does not specify whether the documentation must be youth-specific or can be broader community data.
Is prescription drug misuse also part of the above-average rate documentation requirement?
The explicit documentation requirement described is for opioid misuse and/or methamphetamine use above the national average over a sustained period. Prescription drug misuse is clearly a target of the grant, but it is not explicitly named as part of the above-average documentation requirement in the information provided.
Where must the funded activities take place?
The opportunity is intended to fund coalition activities within the United States. Proposed activities are expected to occur domestically.
Can this grant support work outside the United States?
No. The description states the program does not authorize funding for work outside the U.S.
Where must the applicant organization be located?
The applicant organization must reside in the United States and/or U.S. territories.
Which federal agencies are involved in accepting and administering applications?
The opportunity is situated within the federal drug control and public health landscape. Applications are accepted and administered through the Department of Health and Human Services (HHS) via the Centers for Disease Control and Prevention (CDC), specifically CDC's National Center for Injury Prevention and Control (NCIPC). The Office of National Drug Control Policy (ONDCP) is also noted as part of the program context.
What is the program identifier (RFA number) for this opportunity?
The opportunity is listed as CDC RFA CE 26 0110.
What is the Assistance Listing (CFDA) number?
The Assistance Listing (CFDA) number provided is 93.799.
What is the application deadline?
The application deadline provided is January 21, 2026.
How much funding is available per award (maximum)?
The award ceiling is $75,000 per award.
How many awards are expected?
The opportunity anticipates making about 45 awards.
Is this grant intended to create new coalitions?
The funding is described as an enhancement grant connected to the DFC framework, suggesting it is intended to supplement and sharpen coalition work already underway rather than build brand-new coalitions from scratch.
What laws authorize or relate to this program?
The eligibility is authorized under Section 103 of the Comprehensive Addiction and Recovery Act (CARA) (Public Law 114-198). The DFC Support Program itself was established under the Drug-Free Communities Act of 1997 (Public Law 105-20).
Are there policy or compliance expectations tied to Executive Orders?
Yes. The notice states that, in alignment with the Administration's Statement of Drug Policy Priorities, applicants should be prepared to support applicable Executive Orders referenced in the announcement, and that program planning, policies, and implementation may be expected to align with these federal directives where applicable.
Which Executive Orders are specifically mentioned?
The announcement text mentions Executive Order 14168, Executive Order 14159, Executive Order 14173, Executive Order 13768, and Executive Order 14182.
What should applicants do about the Executive Orders mentioned?
The description indicates applicants should read the full funding announcement carefully to understand any compliance, certification, or assurance requirements that may be tied to those orders and may affect program planning, policies, or implementation.
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